Multistage Detection of Tetrodotoxin Traces in Diodon hystrix Collected in El Salvador

نویسندگان

چکیده

This study describes a multistage methodology to detect minute amounts of tetrodotoxin in fishes, plan that may be broadened include other marine organisms. was applied porcupinefish (Diodon hystrix) collected Punta Chiquirín, El Salvador. A three-stage approach along with post-acquisition processing employed, wit: (a) Sample screening by selected reaction monitoring (HPLC-MS/MS-SRM) analyses quickly identify possible toxin presence via LC/MS/MS API 3200 system triple quadrupole; (b) HPLC-HRFTMS-full scan using an ion trap-Orbitrap spectrometer combined MZmine 2-enhanced dereplication-like workflow collect high-resolution mass spectra; and (c) HPLC-HRMS2 analyses. is the first time has been reported D. hystrix specimens

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ژورنال

عنوان ژورنال: Toxins

سال: 2023

ISSN: ['2072-6651']

DOI: https://doi.org/10.3390/toxins15070409